Bioprocess Technology- Fundamentals and Applications Chapt 4_Metabolic basis(4)

each sugar has its specific membrane bound permease (Enz II) and some sugars also aspecific soluble enzyme which is the last link between Enz II and PEP. For glucose, thissoluble enzyme is called Enz IIIglc. Enz IIIglc has turned out to have a central regulatory rolefor the metabolism of non-PTS-sugars i.e. sugar substrates that are transported by othertransport systems.

Fig. 4.4 The phosphoenolpyruvate: sugar phosphotransferase system of E. coli. Enz I= Enzyme I; Hpr = Heat stable protein; Enz IIIglc = Enzyme III, soluble enzyme,specific for glucose; Enz IIglc = Enzyme II, membrane bound glucose specificpermease.

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