骨科病房骨关节感染部位分离病原体及其耐药性

骨科病房骨关节感染部位分离病原体及其耐药性

李丽;刘海峰

【期刊名称】《中国感染控制杂志》 【年(卷),期】2015(000)001

【摘要】Objective To understand the distribution and antimicrobial resistance of pathogens isolated from bone and joint infection sites of orthopedic patients,so as to provide reference for prevention and therapy of bone and joint infection.Methods 114 specimens from bone and joint infection sites of orthopedic patients between June 2010 and October 2013 were surveyed,pathogens and antimicrobial susceptibility of pathogens were analyzed.Results A total of 145 pathogenic isolates were

obtained,62.07%(n=90)of

which

were

gram-negative

bacteria,34.48%(n=50)were gram-positive bacteria,2.07%(n=3)were

Candida spp .,and 1 .38%(n =2)were anaerobic bacteria. The top 4 pathogens were Pseudomonas aeruginosa (20.69%),Staphylococcus aureus (12.41 %),Escherichia coli (11 .03 %),and Enterobacter cloacae (9.65%).These pathogens presented remarkable resistance.The resistant rate of Pseudomonas aeruginosa to ceftazidime was up to 40.00%;the resistant

rates

of

Escherichia

and

coli

to

com-pound were

all

sulfamethoxazole,ciprofloxacin levofloxacin

100.00%.Conclusion Gram-negative bacteria are the major pathogens in orthopedic ward,the isolated strains are resistant to multiple