PROSTAGLANDIN EP1 RECEPTOR

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申请(专利)号： WO2002JP02757

专利号： WO02077226A1 主分类号： C12N15/10

申请权利人： ONO

PHARMACEUTICAL CO., LTD.; TAJIMA, HISAO 公开国代码： WO 优先权国家： JP

摘要：

(1) A prostaglandin E (PGE) receptor which is a novel polypeptide; (2) a cDNA encoding this polypeptide and a fragment selectively hybridizable with its sequence; (3) a replication or expression vector comprising this DNA; (4) host cells transformed by the replication or expression vector; (5) a process for producing the above polypeptide by culturing these host cells; (6) a

monoclonal or polyclonal antibody against

申请日： 2002-03-22 公开公告日： 2002-10-03

分类号： C12N15/10;

C12P21/02; C12P21/08; C07K14/705; C07K16/28; A61K38/00; A61K39/395; A61P13/02; A61P29/00; A61P43/00; G01N33/15; G01N33/50; G01N33/53; G01N33/566; G01N33/577 发明设计人： TAJIMA, HISAO

申请国代码： JP

优先权： 20010323 JP 2001-85480

摘要附图：

the above polypeptide; (7) medicinal compositions comprising the above polypeptide or the above antibody together with a pharmaceutically

acceptable filler and/or an antibody; and (8) a method of screening a compound having an agonistic or antagonistic activity to EP1. This polypeptide is

usable as remedies for diseases caused by overproduction of PGE2 such as pain, fever and urinary frequency. 主权项：

权利要求说明书

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