联合检测HE4、CA125和CA199对卵巢癌的诊断价值

联合检测HE4、CA125和CA199对卵巢癌的诊断价值

伊学军;翟建新

【期刊名称】《中国社区医师》 【年(卷),期】2015(000)022

【摘要】目的：探讨血清HE4、CA125和CA199联检对卵巢癌的诊断价值。方法：收集卵巢癌患者85例和正常人60例，采用雅培ARCHITECT Plus i2000微粒子免疫化学发光分析仪对血清HE4、CA125和CA199进行测定。结果：卵巢癌组血清 HE4、CA125和 CA199检测结果分别为(118.62±42.34)pmol/mL、(288.3±56.2)U/mL 和(123.±34.5)U/mL，与健康对照组相比差异具有统计学意义(P＜0.01)。卵巢癌组血清 HE4、CA125和 CA199阳性率分别为69.4%、65.9%、52.9%，联合检测阳性率90.6%。结论：血清HE4、CA125和CA199联合检测可提高诊断阳性率，对早期卵巢癌的临床辅助诊断有一定价值。%Objective:To explore the diagnostic value of combined detection of serum HE4、CA125 and CA199 in ovarian cancer. Methods:85 patients with ovarian cancer and 60 cases of normal were selected.Using Abbott ARCHITECT Plus i2000 particles immune chemiluminescence analyzer measured the serum HE4,CA125 and CA199.Results:The serum HE4,CA125 and CA199 detection result of the ovarian

cancer

group

were

respectively

(118.62±42.34)pmol/mL,(288.3±56.2)U/mL and (123.±34.5)U/mL.There had significant differences when compared with the healthy control group(P<0.01).The serum HE4,CA125 and CA199 positive rates of the

ovarian cancer group were respectively 69.4%,65.9%,52.9%,and the positive rate of combined detection was 90.6%.Conclusion:The combined detection of serum HE4,CA125 and CA199 can improve the diagnostic positive rate,and it has certain value for the clinical auxiliary diagnosis of early ovarian cancer. 【总页数】2页(104-105)

【关键词】HE4;CA125;CA199;卵巢癌 【作者】伊学军;翟建新

【作者单位】300193天津中医药大学第一附属医院检验科;300193天津中医药大学第一附属医院检验科 【正文语种】中文 【中图分类】 【文献来源】

https://www.zhangqiaokeyan.com/academic-journal-cn_chinese-community-doctors_thesis/0201214800153.html 【相关文献】

1.CA125、CA199、CEA联合检测在卵巢癌、良性卵巢囊肿诊断中的临床价值 [J], 刘青青; 王姣珍; 马海芬

2.联合检测 CA125、CA199、CA724和 AFP对卵巢癌的诊断价值 [J], 王丽艳 3.CA125、CA199、HE4联合检测在卵巢癌诊断中的应用价值分析 [J], 苏恒学 4.血清CA199、CA125和YKL40联合检测对卵巢癌的诊断价值 [J], 徐艳艳; 高美华

5.CA199、CA125及CEA联合检测诊断卵巢癌的临床价值 [J], 张涛; 程晓军; 张波

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