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GSDME as an executioner of chemotherapy-induced cell death

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GSDME as an executioner of chemotherapy-induced cell death

Xiaoliang Yu;Sudan He;

【期刊名称】《中国科学》 【年(卷),期】2017(000)011

【摘要】<正>Cell death is a crucial process required for development,tissue

homeostasis,and

pathological

cell

loss

in

multicellular organisms.Cell death mainly occurs in two alternative modes:apoptosis or necrosis.Apoptosis is a form of programmed cell death

with

typical

morphological

features,including

cell

shrinkage,chromatin condensation,and DNA fragmentation(Degterev and Yuan,2008).The dying cell is eventually fragmented into membrane-bound apoptotic

【总页数】4页(P.1291-1294) 【关键词】

【作者】Xiaoliang Yu;Sudan He;

【作者单位】Cyrus Tang Hematology Center and Collaborative Innovation Center of Hematology, Jiangsu Institute of Hematology, Soochow University;Cyrus Tang Hematology Center and Collaborative Innovation Center of Hematology, Jiangsu Institute of Hematology, Soochow University; 【正文语种】英文

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