Phytochemical profiling of Artocarpus lakoocha Roxb. leaf methanol extract and its antioxi

Phytochemical profiling of Artocarpus lakoocha Roxb. leaf methanol extract and its antioxidant,

antimicrobial and antioxidative activities

Ekta Bhattacharya; Rajashree Dutta; Swati Chakraborty; Suparna Mandal Biswas

【期刊名称】《亚太热带生物医学杂志：英文版》 【年(卷),期】2019(000)011

【摘要】Objective:To explore the phytochemical profile of Artocarpus lakoocha Roxb.leaves both qualitatively and quantitatively,and validate its

role

as

a

potent

antioxidant

and

antimicrobial

agent.Methods:Extraction and isolation of different compounds were done from the leaves of Artocarpus lakoocha based on solvent fractionation

method.Subsequently,quantitative

and

qualitative

phytochemical profiling along with antioxidant,antimicrobial and antioxidative

activities

were

tested

following

standard

protocols.Results:Among the five fractions,methanol fraction of Artocarpus lakoocha exhibited higher content of phytochemical compounds[phenols=(3175.21±290.43)mg extract,flavonoids=(1173.15±47.52)mg

QE/g

GAE/g dry

extract

dry and

tannins=(923.53±95.21)mg TAE/g dry extract]as compared to other fractions.The methanol fraction showed the highest antioxidant activity in

DPPH

and

ABTS

radical

scavenging

assays

with

IC50

of(111.98±34.20)μg/mL and(138.26±0.66)μg/mL,respectively,and the