血常规、PCT及CRP检测在新生儿败血症早期诊断中的价值

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血常规、PCT及CRP检测在新生儿败血症早期诊断中的价值

作者：万彩红 刘俐

来源：《延边医学》2015年第12期

摘要：目的： 探讨血常规、PCT及CRP检测在新生儿败血症早期诊断中的价值。方法： 选择我院新生儿科收治的败血症患儿，另选取同期我院新生儿科收治的排除感染性疾病的患儿。比较分析新生儿败血症患儿不同阶段及对照患儿，血小板计数、中性杆状粒细胞比率、PCT和CRP水平的变化情况。结果： 与对照组相比，新生儿败血症患儿感染时血小板计数明显降低，中性杆状核粒细胞比率明显提高，感染时PCT和CRP水平明显提高，差异具有统计学意义（P<0.05），而发生感染前和感染控制后血小板计数，中性杆状核粒细胞比率，PCT和CRP水平无明显变化。讨论： 结合实验室血常规、PCT及CRP的检测，对患儿的早期诊断和治疗十分重要的临床指导意义。

关键词：新生儿败血症;血小板;中性杆状核粒细胞;PTC;CRP

Abstract： Objective： To probe into the value of blood test， PCT and CRP in the early diagnosis of neonatal sepsis. Methods： The children patients with neonatal sepsis were selected in our hospital. And children patients with exclusion of infectious diseases during the same period were selected in our hospital. The changes of platelet count， neutrophil neutral rod ratio， PCT and CRP levels of all the children patients at different stages and control group were compared and analyzed. Results： Compared with the control group， the children patients with neonatal sepsis， the platelet count were decreased， granulocyte neutral rod ratio were improved， the PCT and CRP levels were increased significantly at infection， there were difference significant statistically （P <0.05）. The platelet count， granulocyte neutral rod ratio， PCT and CRP levels before and after infection were changed no significant statistically. Conclusions： Combined with laboratory blood test， PCT and CRP testing， it could have very important guidance for early diagnosis and treatment. Keywords： neonatal sepsis; platelet count; granulocyte neutral rod; PCT; CRP

新生儿败血症作为新生儿期严重病症之一，患儿死亡率较高，及时的诊断及有效的治疗减少患儿并发症，降低患儿死亡率的关键所在[1]。因此，通过对新生儿败血症患儿临床特点的分析，以及血常规、CRP、PCT等检测结果的分析，期望能够寻找合适的实验室诊断途径，必将为患儿得到及时有效的治疗提供有利的依据。 1. 材料与方法