血清和胸水中肿瘤标志物对肺癌恶性胸水诊断意义的比较

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程蒿;高巍;雷光焰

【期刊名称】《现代肿瘤医学》【年(卷),期】2014(000)010

【摘要】目的：探讨恶性胸腔积液患者血清和胸水中癌胚抗原（CEA）、癌抗原-125（CA-125）、铁蛋白（Fer-ritin）及神经元特异性烯醇化酶（ NSE）对恶性胸腔积液诊断的临床意义。方法：恶性胸水的肺癌患者共37例，测量其血清和胸水中的CEA、CA-125、铁蛋白、NSE含量，并进行比较。结果：肺癌患者胸水中CEA、CA-125、铁蛋白含量均明显高于血清组（均P<0.05），而胸水和血清中 NSE 比较差异无统计学意义（ P>0.05）。结论：肺癌患者胸水中肿瘤标志物的阳性率要高于血清中。联合检测胸水中肿瘤标志物对于肺癌的诊断意义更大。%Objective:To explore the significance of CEA,CA-125,Ferritin,NSE in serum and hydrothorax of patients with malignant hydrothorax caused by lung cancer. Methods:Measured and compared CEA,CA-125,Fer-ritin,NSE in serum and hydrothorax in 37 patients with malignant hydrothorax caused by lung cancer. Results:In lung cancer group tumor markers in hydrothorax were obviously higher than those in serum. The quantities of CEA,CA-125,Ferritin in hydrothorax were obviously higher than those in serum(P<0. 005),it was no significance for quanti-ties of NSE in hydrothorax and serum(P>0. 05). Conclusion:In malignant hydrothorax caused by lung cancer,the positive rate of tumor markers in hydrothorax was higher than those in serum. There was great

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