The origin of a novel kind of reassortant(H1N2) of influenza A virus

The origin of a novel kind of reassortant (H1N2) of

influenza A virus

作者：郭元吉[1];祁俊林[2];孔利群[3];程小雯[4];董婕[5];王敏[6];张烨[7];郭俊峰[8];吴昆昱[9];

作者机构：[1]Institute of Virology;[2]Chinese Academy of Preventive Medicine;[3]Beijing 100052;[4]China;[5]Centers for Diseases Control and Prevention of Shanghai;[6]Shanghai 200031;[7]Municipal Hygiene and Anti-epidemic Station of Shenzhen;[8]Shenzhen 580020;[9]China; 来源：中国科学 年：2000 卷：000 期：005

页码：P.519-525 页数：7 中图分类：R373 正文语种：CHI

关键词：influenza A virus a novel kind of reassortant origin.

摘要：Genetic analysis of three H1N2 viruses indicated that only HA genes of H1N2 viruses were similar to that of

A/Guangdong/6/91(H1N1) virus (PR8-like strain), while the other seven genes of them were similar to those of H3N2 virus circulating in man in 1995. Therefore, it could be considered that the H1N2 viruses were derived from reassortment between PR8-like strain and H3N2 virus circulating in man in 1995. However, the genomes of H1N2 viruses were very similar to each other. So the H1N2 viruses isolated in 1998 were not derived from new reassortment between PR8-like strain and H3N2