B.a matrix C.a core tablet
D.hydrocolloid layer
5.The drug best suited for incorporation into a sustained release product are:BCD A.those having a fairly slow rate of absorption and excretion
B.those used in the treatment of chronic rather than acute conditions C.those uniformly absorbed from the gastrointestinal tract D.those having relatively small doses
6.The goal of controlled-release technology is toABD A.produce a convenient dosage form
B.produce a self-administered dosage form C.release drug rapidly
D. yield a constant infusion of the drug
7.The advantages of controlled-release technology include:ABCD A.Extended daytime and nighttime activity of the drug B.Potential for reduced incidence of side effects C.Increased patient compliance
D.Potential lower daily cost to patient due to fewer dosage units use 8.Inorganic compounds in parenterals are commonly removed by :BCD A. heat B.distillation C.reverse osmosis D.deionization
9.Polymorphs have the effects on (BCD A.acidity B.solubility
C.dissolution rates
D.physical stability of the product
The physical and chemical data that should be obtained on the drug substance include : ABCDE Q A. pH stability profile Q B. pH solubility profile
Q C. Molecular structure and weight Q D.Particle size and shape Q E. Optical activity
The modification of the parent structure with parenteral drugs can ()正确答案：ABD Q A. increase stability Q B.alter drug solubility C.decrease depot action
Q D.avoid formulation difficulties
A lengthy wet granulation that includes :正确答案：ABCD Q A.blending of dry ingredients Q B.wet massing Q C.screening
Q D.fluidized bed drying
To determine whether a mixture of powdered ingredients is to be tableted directly or if an intervening wet granulation step is to be introduced. This decision is influenced by many factors,
including:正确答案：BCD
A.the solubility of the ingredient of the drug Q B.the flow properties of the granulation; Q C.the tendency of the granulation to segregate.
Q D.the stability of the drug to heat and moisture
必答［多选题Tablet dosage form include?正确答案：ABCD Q A.chewable tablet Q B.lozenges
Q C.sublingual tablet Q D.buccal tablet
Compared to other oral dosage forms, tablets are the manufacturer's dosage form of choice because of正确答案：ABCD Q A.low cost of manufacture
Q B.low cost of package and shipment Q C.increased stability
Q D.increased virtual tamper resistance
［多选题］Drugs can be excreted in (). 正确答案：ABCD Q A.urine Q B.feces Q C.bile D.milk
Drugs may accumulate in various areas of the body as a result of ( )正确答案：BCD A.disolution Q B.binding
Q C.dissolving in fats
Q D.active transport into cells
The factors influence the absorption include: 正确答案：ABCD Q A.solubility of the drug
Q B.the acidity of the drug's environment Q C.blood flow
Q D. the rate of gastric emptying
The route of administraion includes: 正确答案：ABCDE Q A.by mouth
Q B.injecte into the bloodstream or more commonly into the muscle injecte into the muscle Q D.from the rectum Q E.from the eye 必答［多选题］
Antibiotics are produced by various species of microorganisms, including () 正确答案：BCD plant
Q B. fungi
Q C.actinomyces Q D.bacteria
必答［多选题］The sources of drugs include: 正确答案：ABC A.plant source Q B.animal source
Q C.mineral source _ D.any source
Antibiotics are produced by various species of microorganisms, including () A.plant B.fungi C.actinomyces Dbacteria
我的答案：BCD
1.［多选题］The factors influence the absorption include:
A.solubility of the drug B.the acidity of the drug's environment c.blood flow D.the rate of gastric emptying 我的答案：ABCD 2 .［多选题］
The route of administraion includes: A.by mouth
B.injecte into the bloodstream or more commonly into the muscle c.injecte into the muscle D.from the rectum E.from the eye 我的答案：ABCDE 3 .［多选题］
Drugs may accumulate in various areas of the body as a result of ( ) A.disolution B.binding c.dissolving in fats D.active transport into cells
我的答案：BCD 4.［多选题］
Drugs can be excreted in (). A.urine B.feces c.bile D.milk 我的答案：ABCD
To determine whether a mixture of powdered ingredients is to be tableted directly or if an intervening wet granulation step is to be introduced. This decision is influenced by many factors, including:
A.the solubility of the ingredient of the drug B.the flow properties of the granulation;
c.the tendency of the granulation to segregate. D.the stability of the drug to heat and moisture 我的答案：BCD 3 .［多选题］
Tablet dosage form include?
A. chewable tablet B.lozenges c.sublingual tablet D.buccal tablet 我的答案：ABCD
To determine whether a mixture of powdered ingredients is to be tableted directly or if an intervening wet granulation step is to be introduced. This decision is influenced by many factors,
including:
A.the solubility of the ingredient of the drug B.the flow properties of the granulation;
c.the tendency of the granulation to segregate. D.the stability of the drug to heat and moisture 我的答案：BCD ［多选题］
Many existing products continue to be processed by a lengthy wet granulation that includes : A.blending of dry ingredients B.wet massing c.screening
D.fluidized bed drying 我的答案：ABCD ［多选题］
The modification of the parent structure with parenteral drugs can ( ) A.alter drug solubility B.enhance depot action c.decrease pain on injection D.alter formulation 我的答案ABC 3 .［多选题］
This absorption process of intramuscular and subcutaneous administration is determind by ( ) A.physicochemical properties of the drug B.the formulation used
c.extent of vascularity at the site of injection D.distribution of fat in the tissue 我的答案ABCD 2 .［多选题］
The excipients in parenteral products include :
A antioxidants B.inert gases c.lubricants D.protectants ABD
3 .［多选题］
Other aqueous vehicles that may be used in place of sterile water or bacteriostatic water for injection drugs include A.dextrose (5%)
B.electrolyte solsutions. c.sodium chloride(0.9%) D.nutrient solsutions ABCD
4.［多选题］
How to deal with water that are used to reduce microbial growth and to prevent pyrogen formation? A.Filtration B.chilling c.heating
D.Recirculation ABCD
Suspension requires a delicate balance of variables to formulate a product that is easily resuspended and can be injected through an 18- to 21-gauge needle through its shelf life. To achieve these properties it is necessary to select and carefully maintain : A.particle size distribution B.zeta potential
c.rheological properties D.the manufacturing steps ABCD
3 .［多选题］
Carrier systems includeABD A.micropheres B.liposomes c.solutions D.emulsions 4.［多选题］
Concepts in drug delivery that have received increasing attention include:ABC A.drug carrier systems B.implants
c.intravenous infusers D.intramuscular infusers ［多选题］
The goal of controlled-release technology is to ABD A.produce a convenient dosage form
B.produce a self-administered dosage form C.release drug rapidly
D.yield a constant infusion of the drug ［多选题］
The advantages of controlled-release technology include:ABCD A.Extended daytime and nighttime activity of the drug B.Potential for reduced incidence of side effects C.Increased patient compliance
D.Potential lower daily cost to patient due to fewer dosage units used 4.［多选题］
The drug best suited for incorporation into a sustained release product are :BCD A.those having a fairly rapid rate of absorption and excretion B.those having relatively small doses C.those having relatively large doses
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