HBV血清标志物与HBV-DNA联检对乙型肝炎的诊断价
值
朱琳;赵爱淑;郝俊玲
【期刊名称】《中国社区医师》 【年(卷),期】2015(000)001
【摘要】目的：评价乙型肝炎病毒(HBV)血清标志物与HBV-DNA联检对乙型肝炎的诊断价值。方法：用酶联免疫法(ELISA)测定480例乙肝患者的血清标志物，同时用实时荧光定量 PCR(FQ-PCR)检测血清 HBV-DNA 含量。结果：120例HBsAg、HBeAg、HBcAb阳性标本，HBV-DNA的阳性率98.3%(118/120)，平均HBV-DNA含量(786 E+07 IU/mL)；220例 HBsAg、HBeAb、HBcAb 阳性标本，HBV-DNA 阳性率96.4%(212/220)，平均 HBV-DNA 含量(1.18 E+05IU/mL)；140例HBsAg、HBcAb单项或多项阳性的标本，HBV-DNA阳性率85.7%(120/140)，平均HBV-DNA含量(3.16 E+04 IU/ml)；150例HBV血清标志物全阴性的标本中HBV-DNA阳性率2%(3/150)。结论：HBV血清标志物与HBV-DNA均是诊断乙型肝炎的较好指标，两者联检可使诊断更准确，治疗更合理。%Objective:To explore the value of joint inspection of HBV serum markers and HBV-DNA in diagnosis of hepatitis B. Methods:Enzyme linked immunosorbent assay(ELISA) was used to measure the serum markers of 480 cases of patients with hepatitis B,at the same time,real-time fluorescence quantitative PCR(FQ-PCR) was used to detect serum HBV-DNA content. Results:There were 120 cases of HBsAg,HBeAg,HBcAb positive
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