treatment group tumor recession(CR) in 5 cases(16.7%), part of the recession(PRa) 18(60%), partial mild recession(PRb) 6(20%), no degradation(NR), 1(3.3%), tumor size change significantly better than the control group. The treatment group patients 12 months survival rate was 86.7%, higher than that of the control group(70%). The treatment group of 12 months of tumor recurrence rate of 6.7%, lower than that of the control group(26.7%). No obvious adverse complications of the treatment group of 30 patients after operation. Conclusion: Radiofrequency hyperthermia ablation combined with chemotherapy in treatment of advanced non small cell lung cancer and metastatic lung cancer clinical effect is obvious.[Key words] Radio frequency ablation; Chemotherapy; Lung cancer
[First-author’s address] Department of Tumor, Anyang Sixth People's Hospital, Anyang 455000, China.
肺癌是发病率和病死率增长最快、对人群健康和生命威胁最大的恶性肿瘤之一[1-2]。近50年来,许多国家都报道肺癌的发病率和病死率均明显增高,男性肺癌发病率和病死率均占所有恶性肿瘤的第一位,女性发病率占第二位,病死率占第二位[3-4]。高温射频消融(radiofrequency ablation,RFA)治疗中晚期原发性肺癌和转移性肺癌,已取得显著治疗效果,可明显提高患者生存率,具有并发症少、复发率低等优点。但是,RFA治疗后癌细胞残留是肿瘤复发的主要原因,而化疗可以减少肿瘤复发。为此,本研究采用RFA结合化疗对原发性肺癌及转移性肺癌进行治疗,并评估
①安阳市第六人民医院肿瘤内科 河南 安阳 455000②吉林大学第一医院血液肿瘤科 吉林 长春 130021
其临床疗效和安全性。1 资料与方法1.1 一般资料
选取2011年1月至2012年2月在安阳市第六人民医院住院治疗的60例肺部非小细胞型肺癌、肺部转移癌及肺部复发性肺癌患者,按照患者入院时间顺序,将其分为治疗组和对照组,每组30例。治疗组进行RFA结合化疗,对照组进行单纯化疗。所有患者中男性36例,女性24例;年龄30~70岁。两组患者在男女比例以及肺部各种病理类型的非小细胞癌的构成上无统计学差异,具有可比性。
[16] Roth T,Seventer RV,Murphy TK.The effect of
pregabalin on pain-related sleep interference in diabetic peripheral neuropathy or postherpetic neuralgia: a review of nine clinical trials[J].Curr Med Res Opin,2010,26(10):2411-2419.88 ZHONGGUOYIXUEZHUANGBEI
[17] Attal N,Cruccu G,Baron R,et al.EFNS
guidelines on the pharmacological treatment of neuropathic pain:2010 revision[J].Eur J Neurol,2010,17(9):1113-1123.
收稿日期:2014-09-22
搜索“diyifanwen.net”或“第一范文网”即可找到本站免费阅读全部范文。收藏本站方便下次阅读,第一范文网,提供最新资格考试认证高温射频消融结合化疗在治疗肺部肿瘤中的临床研究全文阅读和word下载服务。
相关推荐: