DC+CIK联合化疗治疗晚期非小细胞肺癌的临床疗效评价(3)

义，可以在临床进一步推广。

参考文献

12

孙孙

燕,石远凯.实用肿瘤内科学[M].第5版.北京:人民卫生出版燕,石远凯.实用肿瘤内科学[M].第5版.北京:人民卫生出版社,2009.260.社,2009.80.

3TrottiA,ColevasAD,SetserA,etal.CTCAEv3.0:development

ofacomprehensivegradingsystemfortheadverseeffectsofcan certreatment[J].SeminRadiatOncol,2003,13(3):176-181.4

金懋林.胃癌化学治疗发展和应用[J].中国肿瘤临床,2000,27(10):192-198.

5SumpterK,Harper-WynneC,CunninghamD,etal.Reportof

twoprotocolplannedinterimanalysesinarandomizedmulticen trephaseⅢstudycomparingcapecitabinewithfluorouracilandoxaliplatinwithcisplatininpatientswithadvancedoesophagogas triccancerreceivingECF[J].BrJCancer,2005,92(11):1976-1983.

6VanMeertenE,EskensFA,VanGamerenEC,etal.First-line

treatmentwithoxaliplatinandcapecitabineinpatientswithad vancedormetastaticoesophagealcancer:aphaseⅡstudy[J].BrJCancer,2007,96(9):1348-1352.

7ParkYH,KimBS,RyooBY,etal.AphaseIIstudyofcapecitabi

neplus3-weeklyoxaliplatinasfirst-linetherapyforpatients

withadvancedgastriccancer[J].BrJCancer,2006,94(7):959-963.8KabbinavarFF,HurwitzHI,YiJ,etal.Additionofbevacizumabtofluorouracil-basedfirt-linetreatmentofmetastaticcolorectalcancer:pooledanalysisofcohortsofolderpatientsfromtworan domizedclinicaltrials[J].JClinOncol,2009,27(2):199-205.9PeetersM,PriceT,VanLaethemJL.Anti-epidermalgrowthfac torreceptormonotherapyinthetreatmentofmetastaticcolorectalcancer:wherearewetoday?[J].Oncologist,2009,14(1):29-39.10FolkmanJ.Roleofangiogenesisintumorgrowthandmetastasis[J].SeminOncol,2002,29(6Suppl16):15-18.

11SongHF,LiuXW,ZhangHN,etal.PharmacokineticsofHis-tagrecombinanthumanendostatininRhesusmonkeys[J].ActaPharmacolSin,2005,26(1):124-128.12曲文书,秦书逵,吴

穷,等.重组人血管内皮抑素抑制内皮细胞血

管生成的实验研究[J].临床肿瘤学杂志,2008,13(4):307-312.13林丽珠,周京旭,郑心婷,等.恩度联合化疗治疗晚期复治非小细胞肺癌31例的临床探讨[J].中国肿瘤临床,2009,36(6):316-319.14秦书逵,刘秀峰,王728-735.

（2009-06-17收稿）（2009-08-05修回）

（王展宏校对）

琳,等.重组人血管内皮抑素与化疗联合治疗

肺外晚期恶性肿瘤的临床研究[J].临床肿瘤学杂志,2007,12(10):

（上接第971页）

患者的生存期，提高患者的生活质量。

参考文献

1KimHM,LimJ,ParkSK,etal.Antitumoractivityofcyto

kine-inducedkillercellsagainsthumanlungcancer[J].IntImmu nopharmacol,2007,7(13):1802-1807.2

尤

健,王长利.肺癌的免疫治疗进展[J].中国肿瘤临床,2008,35(17):1015-1017.

3BerzofskyJA,TerabeM,OhS,etal.Progressonnewvaccine

strategiesfortheimmunotherapyandpreventionofcancer[J].JClinInvest,2004,113(11):1515-1525.4Salgaller

265-278.

5MartenA,ZiskeC,SchottkerB,etal.Interactionsbetweenden

driticcellsandcytokine-inducedkillercellsleadtoanactivationofbothpopulations[J].JImmunother,2001,24(6):502-510.6MartenA,RenothS,vonLilienfeld-ToalM,etal.Enhancedlyt

icactivityofcytokine-inducedkillercellsagainstmultiplemyelo macellsafterco-culturewithidiotype-pulseddendriticcells[J].Haematologica,2001,86(10):1029-1037.

7LinnYC,HuiKM.Cytokine-inducedkillercells:NK-likeT

cellswithcytotolyticspecificityagainstleukemia[J].LeukLympho ma,2003,44(9):1457-1462.

ML.

The

development

of

immunotherapies

for

non-smallcelllungcancer[J].ExpertOpinBiolTher,2002,2(3):

8TuyaertsS,AertsJL,CorthalsJ,etal.Currentapproachesinden driticcellgenerationandfutureimplicationsforcancerimmuno therapy[J].1513-1537.

9YuJ,RenX,CaoS,etal.Th1polarizationandapoptosis-induc ingactivityofCD4+T-cellsincytokine-inducedkillersmightfa vortheantitumorcytotoxicityofcytokine-inducedkillersinvivo[J].CancerBiotherRadiopharm,2006,21(3):276-284.

10张志凯,祁岩超.CIK细胞生物学特性及抗肿瘤作用的研究进展[J].世界肿瘤杂志,2008,7(1):52-56.

11BanchereauJ,SteinmanRM.Dendriticcellsandthecontrolofim munity[J].Nature,1998,392(6673):245-252.

12GeW,LiCH,ZhangW,etal.Cocultureofdendriticcellwithcy tokine-inducedkillerresultsinasignificantincreaseincytotoxicactivityofCIKtotumorcellsinvitroandinvivo[J].ZhonghuaXueYeXueZaZhi,2004,25(5):277-280.13曹

水,于津浦,任秀宝,等.CD4＋T细胞在抗肿瘤过继性免疫治

（2009-04-21收稿）（2009-06-22修回）

（王展宏校对）

疗中作用的研究[J].中国肿瘤临床,2005,32(14):795-797.

Cancer

Immunol

Immunother,

2007,

56(10):

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