:通过组织芯片(t i S S U e m i C r o a rr Y,T MA)和免疫组织化学(inununohistochemistry,IHC)技术检测人类表皮生长因子受体2(tluman epidermal growth factor receptor2,Her-2)在胃癌(gastric carcinoma,GC)中的表达,研究胃癌中Her-2表达的临床意义,为胃癌靶向治疗奠定理论基础。方法:构建包含198例胃癌组织和89例正常胃黏膜的组织芯片,分析Her-2表达与临床病理参数之间的相关性及其对预后的影响。
36.Gravalos C;Jimeno A Her-2 in gastric cancer:a new prognostic factor and a novel therapeutictarget[外文期刊] 2008(9)
37.Kang Y;Bang Y;Lordick F Incidence of gastric and gastro-esophageal cancer in the ToGAtrial:correlation with Her-2 positivity 2008
38.Kang Y.Bang Y.Lordick F Incidence of gastric and gastro-esophageal cancer in the ToGAtrial:correlation with Her-2 positivity 2008
39.Berx G;Backer KF;Hofler H Mutations of the human E-cadherin(CDH1) gene[外文期刊] 199840.Berx G.Backer KF.Hofler H Mutations of the human E-cadherin(CDH1) gene 1998
41.Sasano H.Date F.Imatani A Double immunostaining for c-erbB-2 and p53 in human stomach cancercells 1993
42.Sasano H;Date F;Imatani A Double immunostaining for c-erbB-2 and p53 in human stomach cancercells 1993
43.Park DI.Yun JW.Park JH Her-2/neu amplification is an independent prognostic factor in gastriccancer 2006
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